Europium chelates have traditionally been the ‘go-to reagent’ for the development of fluorescent lateral flow tests. In this study, we compared CPNs™ directly with europium chelate and found CPNs™ to be approximately 100x more sensitive when it comes to the detection of low levels of analytes.
Multiple replicates show a consistently strong signal from CPNs™:
- Lateral flow strips run in triplicate for each hCG concentration
- A consistent bright signal from CPNs™ demonstrating higher sensitivity than europium chelate
- Linear CPNs™ signal across four orders of magnitude
Lateral flow strips produce a higher level of signal from CPNs™ compared to europium chelate across concentrations 1ng, 10ng, 100ng, 1μg, 10μg and 100μg.